![]() Ketoconazole 2% cream is the generic name, is in the class of azole antifungals, and is only available with a prescription from your doctor. It is used for the topical (applied to the skin) treatment of tinea corporis (ringworm), tinea cruris (jock itch), tinea pedis (athletes foot), and in the treatment of tinea (pityriasis) versicolor ("sun fungus") it is also used in the treatment of some skin yeast infections and in the treatment of seborrheic dermatitis. © 2022 British Association of Dermatologists.Ketoconazole 2% cream (Nizoral Cream by Janssen, and others) is an antifungal medication used to treat various fungus and yeast infections. Ketoconazole treatment reduced Malassezia and increased fungal diversity to restore skin microbial communities. These changing trends were maintained until 2 weeks post-treatment.įacial SD showed lower fungal diversity accompanied by increased relative abundances of Malassezia and Staphylococcus and decreased relative abundance of Cutibacterium. After ketoconazole treatment, fungal Shannon diversity and the relative abundances of Candida and Aspergillus were significantly increased at the lesional sites, and the relative abundance of Malassezia showed a decreasing trend. Disease diversity was positively correlated with the relative abundances of Malassezia, Staphylococcus and Corynebacterium, while transepidermal water loss was negatively associated with the relative abundance of Cutibacterium. A decreased relative abundance of Cutibacterium and increased abundances of Malassezia and Staphylococcus were found in facial SD. It works by killing the fungus or yeast or preventing its growth. Significantly lower bacterial and fungal diversities were detected at the lesional sites of facial SD compared with HCs. Ketoconazole is used to treat infections caused by a fungus or yeast. ![]() Available products containing ketoconazole include ointments, creams, shampoos, wipes, sprays. For skin and ear infections, ketoconazole is generally applied topically. Ketoconazole can also decrease testosterone production by binding to important receptors in the body. 13 The essential oil of Melaleuca alternifolia inhibited 80 percent of SD isolates at 1.112 mg/ml and 100 percent at 2.225 mg/ml. sympodialis, comparable to MIC 90 of ketoconazole (KTZ) control. The bacterial 16S V3V4 rRNA and fungal internal transcribed spacer 1-5F regions were sequenced, and the microbial community compositions were analysed. This interferes with the infectious potential of the fungus. The leaves of Azadirachta indica exhibited a minimum inhibitory concentration of 90 percent (MIC 90) at 64 mg/mL for M. Skin swabs were collected from SD lesional sites of the cheek at baseline, after ketoconazole treatment and 2 weeks post-treatment. Child 1217 years Apply twice weekly for 24 weeks, leave preparation on for 35 minutes before rinsing. Treatment of seborrhoeic dermatitis and dandruff for ketoconazole To the skin using shampoo. In total, 30 patients with facial SD and 15 age- and sex-matched healthy controls (HCs) were enrolled in this study. Fungal skin infection (not Tinea pedis) for ketoconazole To the skin using cream. ![]() In this prospective cohort study, we used a high-throughput DNA sequencing method to characterize the cutaneous microbial communities of patients with SD before and after topical ketoconazole treatment. Ketoconazole is commonly used for the treatment of SD however, there are limited data focusing on the effects of ketoconazole in shaping the skin microbiome in patients with SD. Current theories on the pathogenesis of SD highlight the role of microbes on the skin surface. Ketoconazole topical (for the skin) is an antifungal medicine used to treat infections such as athletes foot, jock itch, ringworm, and seborrhea (dry, flaking skin or. ![]() Seborrhoeic dermatitis (SD) is a common chronic inflammatory dermatosis. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |